3,4-Difluoronitrobenzene is a unique chemical structure characterized by a benzene ring substituted with two fluorine atoms at the 3 and 4 positions, along with a nitro group (-NO2) attached to the ring. This compound demonstrates notable reactivity due to the electron-withdrawing nature of both the fluorine and nitro groups. The presence of these substituents generates an increase in electrophilicity, making the benzene ring more susceptible to nucleophilic attack. Therefore, 3,4-difluoronitrobenzene serves as a valuable intermediate in the synthesis of various organic compounds, particularly those with biological applications.
- Its physical properties include a melting point of approximately 48 degrees Celsius and a boiling point of around 192 degrees Celsius.
- Moreover, it exhibits limited solubility in water but is dissolvable in common organic solvents.
The synthesis of 3,4-difluoronitrobenzene typically requires a multi-step process that includes the nitration of fluorobenzene followed by selective fluorination. This compound has been thoroughly examined due to its potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Synthesis and Properties of 3,4-Difluoronitrobenzene
3,4-Difluoronitrobenzene is a significant role in the realm of organic synthesis due to its unique structural characteristics. The synthesis of this compound can be achieved through various routes, with a commonly employed method involving the nitration of 1,2-difluorobenzene. This reaction typically utilizes a mixture of nitric acid and sulfuric acid as the nitrating agent, generating the desired 3,4-difluoronitrobenzene product.
The resulting compound exhibits distinct physicochemical properties that influence its reactivity and applications. Notably, the electron-withdrawing nature of the nitro group in 3,4-difluoronitrobenzene alters its electrophilicity, making it susceptible to nucleophilic attack. This property renders it a versatile building block for the synthesis of complex organic molecules.
- Additionally, the presence of fluorine atoms in the molecule contributes to its resilience and dissolvability in various solvents.
CAS No. for 3,4-Difluoronitrobenzene: Identifying This Compound
When working with chemicals, accurately recognizing them is crucial for safety and correct results. A key tool in this process is the CAS Registry Number, a unique identifier assigned to every chemical compound. For 3,4-Difluoronitrobenzene, this number is vital for ensuring you are working with the correct substance.
The CAS No. for 3,4-Difluoronitrobenzene is 105387-96-3. This alphanumeric identifier can be used to locate information about the compound in databases and research materials. Understanding its properties, hazards, and safe handling procedures is crucial when dealing with this chemical.
Applications of 3,4-Difluoronitrobenzene in Research
3,4-Difluoronitrobenzene exhibits a extensive range of applications in research. Its unique structure and chemical properties permit it to be utilized as a valuable intermediate in the synthesis of novel organic compounds. Researchers utilize 3,4-difluoronitrobenzene for its adaptability in producing new materials with desired properties. Furthermore, this compound functions as a useful tool in the study of physical reactions. Its possibilities extend various research areas, including organic chemistry.
Safety Considerations for Handling 3,4-Difluoronitrobenzene
When working with 3,4-difluoronitrobenzene, it is essential to prioritize personal protection. This substance can be dangerous if not handled properly. Always carry out procedures in a well-ventilated region and don appropriate protective clothing, including chemical resistant gloves, safety glasses, and a lab coat.
Before handling with 3,4-difluoronitrobenzene, carefully review the material safety data sheet (MSDS) provided by the provider. This document will provide comprehensive instructions on potential threats, first aid, and containment procedures.
- Avoid interaction with mucous membranes. In the event of incidence, immediately flush the affected area with copious amounts of clean water for at least 15 minutes.
- Preserve 3,4-difluoronitrobenzene in a tempered location away from heat sources and potentially reactive substances.
- Eliminate of 3,4-difluoronitrobenzene along with packaging in accordance with environmental guidelines.
Spectral Characterization of 3,4-Difluoronitrobenzene
A spectral characterization of this fluorinated nitroarene is crucial for comprehending its chemical properties and potential applications.
IR|UV-Vis|NMR spectroscopy provides valuable insight into the vibrational modes, electronic transitions, and molecular structure of this compound.
The characteristic spectral features observed may be assigned to the presence of the nitro group, fluorine atoms, and benzene ring. Additional spectral analysis highlights the influence of these substituents on the overall molecular environment.
This in-depth spectral characterization 4-Difluoro Nitrobenzene enhances our knowledge of DFNB and its potential function in various chemical reactions.